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The Dangers of Mixing Prozac and Adderall

by | Last updated Feb 18, 2021 at 12:05PM | Published on Feb 18, 2021 | Drug Addiction

prozac and adderall

In the world of prescription medications, so many people tend to mix substances without realizing the side effects of doing this. Among some of the most dangerous combinations is the practice of mixing Prozac and Adderall. Both can help with different behavioral problems, but when combined, both can lead to fatal consequences. 

What is Prozac?

Prozac is one of the most popular brand names for fluoxetine. It works by reuptake serotonin in the brain to increase its effects. Prozac can help with depression, panic disorder, obsessive-compulsive disorder (OCD), bulimia, eating disorders, and other psychiatric disorders. 

What is Adderall?

Adderall is a prescription stimulant medication under the category of stimulants. It operates similarly to other addictive drugs like meth. Adderall increases dopamine and norepinephrine levels in the central nervous system. Indeed, most doctors prescribe Adderall to treat attention deficit hyperactivity disorder (ADHD) and narcolepsy. However, some people fake symptoms to get prescription medication.

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How Dangerous is Mixing Prozac and Adderall?

The active components in Prozac and Adderall have major drug interactions. When people miz fluoxetine (Prozac) and amphetamines or dextroamphetamine (Adderall), the adverse effects can be catastrophic. 

Adderall is a stimulant, but its chemical makeup interacts with the chemical pathway of Prozac and vice versa. The danger of mixing Prozac and Adderall is that they sort of null each other. So, when people combine these drugs, Prozac blocks amphetamines and makes it a lot easier for people to overdose. 

Side effects of this combination include jitteriness, anxiety, nervousness, restlessness, and racing thoughts. It also increases the risk of developing serotonin syndrome, which causes confusion, seizures, hallucinations, and extreme changes in blood pressure, heart rate, fever, and shivering. Severe cases of serotonin syndrome can result in coma and even death. 

Polysubstance Abuse Treatment Options

Polysubstance abuse is a unique issue that often involves a substance use disorder with a mental health condition. Unfortunately, it wasn’t until recently that most rehab centers started to treat these conditions simultaneously. The level of depressive and somatic symptoms of polysubstance users indicates a need for mental health screening before treating addiction. A comprehensive treatment plan needs to incorporate different treatment modalities and approaches to addressing polysubstance abuse as a whole. 

Drug and Alcohol Detox

The first step toward recovery is detox. When people start mixing Prozac and Adderall, attempting to quit independently, they can experience side effects that can be life-threatening. To avoid overdose and fatal withdrawal symptoms like seizures, checking into a detox rehab center is paramount. With supervision from a medical professional, recovering drug addicts can have a better chance of sobriety. 

Drug and Alcohol Rehab

After detox, most patients will move either to an inpatient treatment program that offers structure and support 24/7. Others, mostly those with less severe addictions, might be able to choose an intensive outpatient program that provides more flexibility so that they can continue daily responsibilities like work, school, and family. 

Aftercare Recovery Programs

Unfortunately, addiction is a life-long condition. Aftercare recovery programs offer continuing support once people leave a rehab facility. Here, patients focus on building life development skills that help them integrate back into society. Most people keep working on relapse prevention coping mechanisms that allow them to sustain long-term sobriety. 

Seeking Addiction Help Today

If you or someone you know is struggling with substance abuse disorders, please contact us today. Whether that involves a complete drug and alcohol detox process, intensive outpatient treatment, or continuous aftercare support, we’ll do everything in our power to help you beat this chronic disease.

If you know someone who’s mixing Percocet and Adderall, reach out to them and see if they’re ready to get help for their addiction. Also, if you need help setting up an intervention, our addiction specialists can offer counsel and guidance.

At Lighthouse Recovery Institute, our addiction specialists can help you find the best treatment program for your unique needs. Besides, we don’t believe in cookie-cutter treatment plans, which is why we look at each case on an individual basis and do our absolute best to accommodate your needs to help your recovery journey. 

NIDA. 2020, October 14. How is methamphetamine different from other stimulants, such as cocaine?. Retrieved from on 2021, March 12

NIDA. 2020, September 8. What are the long-term effects of methamphetamine misuse?. Retrieved from on 2021, March 12

Sussman, S., Pentz, M. A., Spruijt-Metz, D., & Miller, T. (2006). Misuse of “study drugs:” prevalence, consequences, and implications for policy. Substance abuse treatment, prevention, and policy, 1, 15.

NIDA. 2018, June 6. Prescription Stimulants DrugFacts. Retrieved from on 2021, March 12

Geraldine Orentas

Geraldine Orentas

Geraldine is Lighthouse Recovery Institute’s Digital Marketing Manager. She has a Bachelor’s in Journalism and experience in the digital media industry. Geraldine’s writing allows her to share valuable information about mental health, wellness, and drug addiction facts, hoping to shed light on the importance of therapy and ending the stigma.
Medical Disclaimer:

Lighthouse Recovery Institute aims to improve the quality of life for anyone struggling with substance use or mental health disorder. We provide fact-based content about the nature of behavioral health conditions, treatment options, and their outcomes. The material we publish is researched, cited, edited, and reviewed by licensed medical professionals. The information we provide in our posts is not intended to be a substitute for professional medical advice, diagnosis, or treatment. It should never be used in place of the advice of your physician or another qualified healthcare provider.

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